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What is Major Histocompatibility complex (MHC) or Human Leukocyte Antigen( HLA)? • Cluster of highly polymorphic genes present in short arm of chromosome . • Product of which is associated with various functions in immune response particularly in rejection or acceptance of foreign tissue in a host. • They are alloantigen. • The Major Histocompatibility […]
Adjuvant They are substances that when mixed with an antigen & injected with it, enhance the immunogenicity of that antigen. They are used when an antigen has low immunogenicity or when only small amounts of an antigen are available. • Aluminum potassium sulfate (Alum)is the only adjuvant approved for human use. • Effect of adjuvants […]
Complement is an essential component of our innate host defences. Complement is a collective term used to designate a group of plasma proteins at least 20 in number, that are present in average human (and other animals) serum. The term “complement” refers to the ability of these proteins to complement, i.e., augment, the effects of […]
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