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What is Major Histocompatibility complex (MHC) or Human Leukocyte Antigen( HLA)? • Cluster of highly polymorphic genes present in short arm of chromosome . • Product of which is associated with various functions in immune response particularly in rejection or acceptance of foreign tissue in a host. • They are alloantigen. • The Major Histocompatibility […]
Immunoglobulin are proteins of animal origin endowed with or without antibody activity. So structurally related proteins without antibody activity are also known as immunoglobulin, e.g. myeloma protein (found in multiple myeloma). Antibody Antibodies are glycoprotein substances synthesized and secreted by B lymphoid lineage cells, termed plasma cells, in response to stimulation with an immunogen. Basic […]
Adjuvant They are substances that when mixed with an antigen & injected with it, enhance the immunogenicity of that antigen. They are used when an antigen has low immunogenicity or when only small amounts of an antigen are available. • Aluminum potassium sulfate (Alum)is the only adjuvant approved for human use. • Effect of adjuvants […]
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